Januvia, Galvus, Onglyza, Trajenta, Nesina (DPP-4 Inhibitors)
* Approved in Europe, Japan, China; not approved in USA
|Brand Name ||Generic Name |
** Approved in Japan and USA
What does this type of pill do?
This type of pill lowers your blood glucose by helping your body make more insulin when it's needed, especially right after meals. It also helps keep your liver from putting stored glucose into your blood.
Who should not take DPP-4 Inhibitors?
Talk with your doctor about whether to take this type of pill if
- you are pregnant, planning to get pregnant, or breastfeeding
- you have kidney disease
- you have
type 1 diabetes
and if you have [had] a condition called diabetic ketoacidosis
What are the possible side effects?
This type of pill doesn't cause low blood glucose by itself. But your risk of having low blood glucose goes up if you also take
- diabetes pills that cause low blood glucose
Your doctor may ask you to take a lower dose of your other diabetes medicines while you take this type of pill.
Possible side effects are
- a cold
- runny nose
- sore throat
If you take DPP-4 Inhibitors and have kidney problems,
your health care provider might order blood tests to see how well your kidneys are working.
The DPP-4 inhibitors may contribute to the development of pancreatitis or pancreatic cancer.
American Diabetes Association Calls for Independent Review of Incretin Therapy (June 10, 2013).